Everything works out of the box, and it doesn't use a third party layer like MicroG. The difference is that Google's apps/services are not given admin privileges like they usually are, so you can selectively enable or disable things.

For example, installing an app on Google Play works like F-Droid. Once the download finishes, you have to open the Play store app to trigger a system dialog to accept the installation. On other Android devices, GPlay can install apps without your approval.