The only time megadosing B12 is a good idea is if you have confirmed low levels via a blood test and need to quickly raise your levels to the normal range.
Don’t assume you can guess your B12 status by reading random articles on the Internet. Low B12 has become a favorite hypothesis among the alternate medicine crowd, so online information about B12 supplementation has become corrupted with pseudoscience.
I’ll admit that I fell for the idea that B12 deficiency was rampant due to modern diets. Then I got a blood test and discovered that my B12 levels were toward the upper end of the reference range already.
On the bright side, B12 absorption is very nonlinear. A megadose might only cause slightly more absorption than what you find in a regular multivitamin. Most of the megadose is simply not absorbed.
For example, elevated B12 levels are associated with increased lung cancer risk in a dose-response fashion: https://pubmed.ncbi.nlm.nih.gov/30499135/
The only time megadosing B12 is a good idea is if you have confirmed low levels via a blood test and need to quickly raise your levels to the normal range.
Don’t assume you can guess your B12 status by reading random articles on the Internet. Low B12 has become a favorite hypothesis among the alternate medicine crowd, so online information about B12 supplementation has become corrupted with pseudoscience.
I’ll admit that I fell for the idea that B12 deficiency was rampant due to modern diets. Then I got a blood test and discovered that my B12 levels were toward the upper end of the reference range already.
On the bright side, B12 absorption is very nonlinear. A megadose might only cause slightly more absorption than what you find in a regular multivitamin. Most of the megadose is simply not absorbed.